Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380831 | 0.98 | MIF (0.45) | MIFNAAAOPRM1OPRD1OPRK1 | |
| SCHEMBL6744506 | 0.86 | MIF (0.49) | MIFOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17274465 | 0.84 | MIF (0.65) | MIFNAAAOPRM1OPRD1OPRK1 | |
| SCHEMBL11231906 | 0.83 | CYP3A4 (0.39) | PRSS1PRSS2PRSS3 | |
| SCHEMBL4304143 | 0.82 | MIF (0.45) | MIFNAAAOPRM1OPRD1OPRK1 | |
| SCHEMBL7808 | 0.82 | MIF (0.67) | MIFNAAAOPRM1OPRD1OPRK1 | |
| SCHEMBL6970517 | 0.79 | MIF (0.67) | MIFPOLBMEN1KMT2A | |
| SCHEMBL957752 | 0.79 | MIF (0.67) | MIFPOLBMEN1KMT2A | |
| SCHEMBL727626 | 0.79 | MIF (0.67) | MIFPOLBMEN1KMT2A | |
| SCHEMBL22444459 | 0.79 | TSHR (0.40) | NAAAPRSS1PRSS2PRSS3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317756-A | Sizing composition comprising a hydrophobic cellulose-reactive sizing agent and a cationic polymer | HERCULES INCORPORATED (US) | 1982-03-02 | — | — | US | disclosed |