Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2194475 | 0.71 | POLB (0.50) | POLBCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL12816345 | 0.71 | POLB (0.35) | POLBCYP1A2 | |
| SCHEMBL8951150 | 0.70 | POLB (0.35) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10482328 | 0.67 | PIM1 (0.39) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27653072 | 0.67 | POLB (1.00) | POLBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28187478 | 0.65 | POLB (0.39) | POLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL3688105 | 0.65 | POLB (0.39) | POLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL28385010 | 0.62 | POLB (0.43) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11307975 | 0.60 | POLB (0.41) | POLBCYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL1004648 | 0.60 | POLB (0.55) | POLBALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353923-A | MUSCLE RELAXANTS, ANTIINFLAMMATORY, ANALGESIC | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1982-10-12 | — | — | US | disclosed |