Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 13/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.53 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123965 | 0.79 | DHODH (0.74) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL1336884 | 0.76 | DHODH (0.78) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL517692 | 0.75 | DHODH (1.00) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL28602602 | 0.72 | DHODH (0.55) | DHODHSMN1; SMN2 | |
| SCHEMBL2271137 | 0.71 | HDAC2 (0.74) | DHODHRAB9ASMN1; SMN2NPC1HDAC2 | |
| Vidofludimus SCHEMBL29352865 | 0.70 | DHODH (1.00) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| Vidofludimus SCHEMBL247888 | 0.70 | DHODH (1.00) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL14418145 | 0.69 | DHODH (0.67) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| Vidofludimus SCHEMBL28974266 | 0.69 | DHODH (0.98) | DHODHNR4A2JMJD7NR4A1NR4A3 | |
| SCHEMBL14418192 | 0.69 | DHODH (0.73) | DHODHNR4A2JMJD7NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283898-A1 | Aromatic compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2011-02-16 | — | — | EP | disclosed |