Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.73 |
| ▸ | MGLL | Q99685 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246226 | 1.00 | POLB (0.76) | POLBSMPD1MGLLHDAC3HDAC2 | |
| SCHEMBL3880413 | 1.00 | POLB (0.76) | POLBSMPD1MGLLHDAC3HDAC2 | |
| SCHEMBL931440 | 0.99 | POLB (0.73) | POLBSMPD1MGLLHDAC3HDAC2 | |
| SCHEMBL6356934 | 0.94 | HDAC3 (0.74) | POLBSMPD1MGLLHDAC3HDAC2 | |
| SCHEMBL11761148 | 0.94 | POLB (0.84) | POLBSMPD1HDAC3HDAC2MEN1 | |
| Hydrochloric Acid SCHEMBL9639590 | 0.93 | HDAC3 (0.72) | POLBSMPD1MGLLHDAC3HDAC2 | |
| SCHEMBL2800438 | 0.89 | SMPD1 (0.62) | POLBSMPD1MGLLMEN1KMT2A | |
| SCHEMBL598032 | 0.89 | SMPD1 (0.62) | POLBSMPD1MGLLMEN1KMT2A | |
| SCHEMBL10958244 | 0.89 | SMPD1 (0.62) | POLBSMPD1MGLLMEN1KMT2A | |
| SCHEMBL28907470 | 0.89 | POLB (0.76) | POLBSMPD1HDAC3HDAC2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342875-A | STABILIZERS FOR OLEFIN POLYMERS | CINCINNATI-MILACRON, INC. (US) | 1982-08-03 | — | — | US | disclosed |