Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CD74 | P04233 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22144862 | 0.83 | CYP19A1 (0.47) | MEN1KMT2AALDH1A1NTSR1CYP19A1 | |
| SCHEMBL11247139 | 0.79 | ESR1 (0.65) | MEN1KMT2AALDH1A1NTSR1MMP3 | |
| SCHEMBL1029039 | 0.78 | PLAU (0.52) | MEN1KMT2AALDH1A1NOTUMMMP3 | |
| SCHEMBL2118725 | 0.78 | MEN1 (0.59) | MEN1KMT2AALDH1A1NTSR1NOTUM | |
| SCHEMBL31245685 | 0.78 | PLAU (0.52) | MEN1KMT2AALDH1A1NOTUMMMP3 | |
| SCHEMBL23239956 | 0.78 | KDM4E (0.50) | ALDH1A1CYP19A1RAB9AMAPTNPC1 | |
| SCHEMBL22208326 | 0.78 | MAPT (0.54) | MEN1KMT2AALDH1A1NTSR1CYP19A1 | |
| SCHEMBL20870697 | 0.78 | MEN1 (0.53) | MEN1KMT2AALDH1A1NTSR1RAB9A | |
| SCHEMBL7381995 | 0.78 | MEN1 (0.53) | MEN1KMT2AALDH1A1NTSR1MMP3 | |
| SCHEMBL18760499 | 0.77 | MEN1 (0.57) | MEN1KMT2AALDH1A1NTSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200216394-A1 | Small Molecule Lipid II Inhibitors | UNIVERSITY OF MARYLAND, BALTIMORE | 2020-07-09 | — | — | US | disclosed |
| EP-0013936-B1 | REACTIVE AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE IN DYEING MATERIALS CONTAINING HYDROXYL GROUPS AND AMIDE GROUPS | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| US-4327018-A | Azo dyes and the production and use thereof | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |
| US-4299764-A | Azo reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-10 | — | — | US | disclosed |
| EP-0013936-A1 | Reactive azo dyestuffs, their preparation and their use in dyeing materials containing hydroxyl groups and amide groups | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |
| US-4160643-A | FOR POLYMERS OF ACRYLONITRILE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-10 | — | — | US | disclosed |
| US-4079052-A | Diazopigments containing pyridine derivatives | CIBA-GEIGY CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200216394-A1 | Small Molecule Lipid II Inhibitors | DBI, FABP2, HDLBP | CRHBP 1988/4885CRHR2 3238/4885MEN1 1964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.