Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | JMJD7 | P0C870 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247844 | 0.87 | NPC1 (0.46) | KMT2ANPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL11251672 | 0.85 | DHODH (0.58) | KMT2ANPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL11246036 | 0.84 | DHODH (0.45) | KMT2ANPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL11230959 | 0.84 | NPSR1 (0.65) | KMT2ANPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL11227353 | 0.84 | DHODH (0.50) | KMT2ANPC1RAB9AHPGDSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL11680028 | 0.83 | NPSR1 (0.64) | KMT2ANPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL11219278 | 0.83 | KMT2A (0.51) | KMT2ANPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL11413240 | 0.81 | NPSR1 (0.57) | KMT2ANPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL11236589 | 0.80 | KMT2A (0.48) | KMT2ANPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL11401544 | 0.80 | DHODH (0.46) | KMT2ANPC1RAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362546-A | Tetrahydrophthalamide derivatives, herbicidal compositions and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-12-07 | — | — | US | disclosed |