Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11190170 | 1.00 | SPHK1 (0.50) | SPHK1CYP2C9MAPTGAAALDH1A1 | |
| SCHEMBL11188896 | 1.00 | SPHK1 (0.50) | SPHK1CYP2C9MAPTGAAALDH1A1 | |
| SCHEMBL11241897 | 1.00 | SPHK1 (0.50) | SPHK1CYP2C9MAPTGAAALDH1A1 | |
| SCHEMBL11191518 | 1.00 | SPHK1 (0.50) | SPHK1CYP2C9MAPTGAAALDH1A1 | |
| SCHEMBL11191523 | 1.00 | SPHK1 (0.50) | SPHK1CYP2C9MAPTGAAALDH1A1 | |
| SCHEMBL11198137 | 1.00 | SPHK1 (0.50) | SPHK1CYP2C9MAPTGAAALDH1A1 | |
| SCHEMBL11190177 | 1.00 | SPHK1 (0.50) | SPHK1CYP2C9MAPTGAAALDH1A1 | |
| SCHEMBL11196951 | 1.00 | SPHK1 (0.50) | SPHK1CYP2C9MAPTGAAALDH1A1 | |
| SCHEMBL11190738 | 1.00 | SPHK1 (0.50) | SPHK1CYP2C9MAPTGAAALDH1A1 | |
| SCHEMBL11196945 | 1.00 | SPHK1 (0.50) | SPHK1CYP2C9MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030277-B1 | PARTIALLY HYDROGENATED OLIGO-1,4-PHENYLENES, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING DEVICE | MERCK PATENT GmbH (DE) | 1983-07-27 | — | — | EP | disclosed |
| US-4331552-A | Liquid crystalline, partially hydrogenated oligo-1,4-phenylenes and dielectrics and electro-optical display elements containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-25 | — | — | US | disclosed |
| EP-0030277-A1 | Partially hydrogenated oligo-1,4-phenylenes, dielectrics containing them and electro-optical indicating device | MERCK PATENT GmbH (DE) | 1981-06-17 | — | — | EP | disclosed |