Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.52 |
| ▸ | ARG1 | P05089 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 5/20 | 0.42 |
| ▸ | MASP2 | O00187 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242285 | 1.00 | GRIK1 (0.52) | GRIK1ARG1HRH3F2MASP2 | |
| SCHEMBL30471675 | 0.87 | F2 (0.43) | GRIK1HRH3F2MASP2 | |
| SCHEMBL3190846 | 0.86 | HRH3 (0.54) | GRIK1ARG1HRH3F2MASP2 | |
| SCHEMBL22536533 | 0.86 | HRH3 (0.54) | GRIK1ARG1HRH3F2MASP2 | |
| SCHEMBL931868 | 0.86 | HRH3 (0.54) | GRIK1ARG1HRH3F2MASP2 | |
| SCHEMBL19292680 | 0.86 | HRH3 (0.54) | GRIK1ARG1HRH3F2MASP2 | |
| SCHEMBL199035 | 0.86 | HRH3 (0.54) | GRIK1ARG1HRH3F2MASP2 | |
| SCHEMBL199034 | 0.86 | HRH3 (0.54) | GRIK1ARG1HRH3F2MASP2 | |
| SCHEMBL1706921 | 0.86 | HRH3 (0.54) | GRIK1ARG1HRH3F2MASP2 | |
| Hydrochloric Acid SCHEMBL11237072 | 0.86 | GRIK1 (0.42) | GRIK1ARG1HRH3F2MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113967258-B | FAP-activated therapeutic agents and related uses | 塔夫茨大学信托人 | 2024-07-02 | — | — | CN | disclosed |
| EP-4013440-A1 | THERAPEUTIC PEPTIDES | Cohbar Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| CN-114269367-A | Therapeutic peptides | 科巴公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-113967258-A | FAP-activated therapeutics and uses related thereto | 塔夫茨大学信托人 | 2022-01-25 | — | — | CN | disclosed |
| CN-113956325-A | FAP-activated therapeutics and uses related thereto | 塔夫茨大学信托人 | 2022-01-21 | — | — | CN | disclosed |
| EP-3668886-A2 | TAU AGGREGATION PEPTIDE INHIBITORS | Adrx, Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019036725-A2 | TAU AGGREGATION PEPTIDE INHIBITORS | ADRX, INC. (US) | 2019-02-21 | — | — | WO | disclosed |
| US-4316905-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |