Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.41 |
| ▸ | WNT3A | P56704 | 6/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | EPM2A | O95278 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10631894 | 0.87 | HSD17B10 (0.49) | HTR1BCYP2A6FFAR1CTNNB1WNT3A | |
| SCHEMBL13227110 | 0.79 | HTR1B (0.39) | HTR1BCYP2A6FFAR1CTNNB1WNT3A | |
| SCHEMBL20023702 | 0.75 | HTR1B (0.46) | HTR1BCYP2A6FFAR1DYRK1ACDK9 | |
| SCHEMBL28459447 | 0.75 | HTR1B (0.46) | HTR1BCYP2A6FFAR1DYRK1ACDK9 | |
| SCHEMBL7524832 | 0.75 | CTNNB1 (0.43) | HTR1BCYP2A6FFAR1CTNNB1WNT3A | |
| SCHEMBL31023860 | 0.74 | CYP2A6 (0.46) | HTR1BCYP2A6FFAR1CTNNB1WNT3A | |
| SCHEMBL12087093 | 0.72 | DYRK1A (0.41) | HTR1BCYP2A6FFAR1CTNNB1WNT3A | |
| SCHEMBL8120372 | 0.72 | UGT2B7 (0.50) | PLAU | |
| SCHEMBL3441414 | 0.72 | AR (0.61) | HTR1BCYP2A6CTNNB1WNT3AAR | |
| SCHEMBL31295594 | 0.72 | UGT2B7 (0.50) | HTR1BCYP2A6FFAR1CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341792-A | ANTIDIABETIC AND CARDIOTONIC AGENTS | PFIZER INC. (US) | 1982-07-27 | — | — | US | disclosed |