Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | PTGDR2 | Q9Y5Y4 | 14/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL508552 | 0.89 | PTGDR2 (0.58) | PTGDR2 | |
| SCHEMBL509141 | 0.88 | GAA (0.64) | GAAPTGDR2POLBNPC1LMNA | |
| SCHEMBL31395711 | 0.87 | PTGDR2 (0.52) | GAAPTGDR2MAPK1 | |
| SCHEMBL509015 | 0.85 | PTGDR2 (0.81) | GAAPTGDR2POLB | |
| SCHEMBL31395608 | 0.83 | PDE4A (0.53) | PTGDR2LMNA | |
| SCHEMBL31395775 | 0.81 | PTGDR2 (0.58) | PTGDR2 | |
| SCHEMBL508498 | 0.81 | PTGDR2 (0.56) | PTGDR2 | |
| SCHEMBL31395807 | 0.80 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL31395823 | 0.80 | PTGDR2 (0.61) | PTGDR2 | |
| SCHEMBL11243796 | 0.78 | PDE4D (0.63) | GAAALDH1A1NPC1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |