Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772930 | 0.86 | CA1 (0.51) | CA1CA2BCHEACHECYP3A4 | |
| SCHEMBL116422 | 0.85 | CA1 (0.43) | CA1CA2BCHEACHECYP3A4 | |
| Methane SCHEMBL27447083 | 0.80 | CA1 (0.44) | CA1CA2BCHEACHECYP3A4 | |
| SCHEMBL10619163 | 0.80 | CYP3A4 (0.64) | CA1CA2BCHEACHECYP3A4 | |
| SCHEMBL9242550 | 0.79 | BLM (0.39) | CA1CA2BCHEACHECYP3A4 | |
| SCHEMBL1726069 | 0.78 | MEN1 (0.56) | MEN1KMT2A | |
| SCHEMBL10782981 | 0.75 | MEN1 (0.50) | CA1CA2BCHEACHEMEN1 | |
| SCHEMBL1726270 | 0.74 | MEN1 (0.56) | MEN1KMT2A | |
| SCHEMBL7772922 | 0.73 | KMT2A (0.46) | CA1CA2BCHEACHEMEN1 | |
| SCHEMBL11889545 | 0.72 | CYP3A4 (0.52) | CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4304778-A | 4-Aminoquinazoline derivatives having fungicidal, anti-insect and acaricidal properties | SANKYO COMPANY LIMITED (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4279908-A | Pyridazine derivatives and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1981-07-21 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |
| US-4052395-A | AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES | SANKYO COMPANY LIMITED (JA) | 1977-10-04 | — | — | US | disclosed |