Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 13/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | IDE | P14735 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11246907 | 0.98 | JAK2 (0.47) | JAK2THRBDHODHNPC1TYMP | |
| SCHEMBL11250095 | 0.81 | JAK2 (0.48) | JAK2THRBDHODHNPC1NSD2 | |
| SCHEMBL1270735 | 0.77 | JAK2 (0.57) | JAK2THRBDHODHTYMP | |
| SCHEMBL122310 | 0.70 | JAK2 (0.57) | JAK2THRBDHODHTYMP | |
| SCHEMBL2894307 | 0.70 | JAK2 (0.57) | JAK2THRBDHODHNPC1TYMP | |
| SCHEMBL22783664 | 0.70 | JAK2 (0.61) | JAK2THRBDHODHNSD2ABL1 | |
| SCHEMBL25391975 | 0.67 | JAK2 (0.59) | JAK2THRBDHODH | |
| SCHEMBL10962665 | 0.67 | JAK2 (0.59) | JAK2THRBDHODHNPC1TYMP | |
| SCHEMBL9715507 | 0.66 | JAK2 (1.00) | JAK2THRBDHODHNPC1TYMP | |
| SCHEMBL8148038 | 0.66 | JAK2 (0.57) | JAK2THRBDHODHNPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052341-A1 | Orotic acid derivatives and their use as agricultural chemicals | UBE INDUSTRIES, LTD. (JP) | 1982-05-26 | — | — | EP | claimed |
| EP-0052341-A1 | Orotic acid derivatives and their use as agricultural chemicals | UBE INDUSTRIES, LTD. (JP) | 1982-05-26 | — | — | EP | disclosed |