SCHEMBL11243378

SCHEMBL11243378

O=C(O)C(CS)N1CSc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.43
FNTB P49356 2/20 0.43
NOTUM Q6P988 1/20 0.37
ACE P12821 2/20 0.36
KMT2A Q03164 2/20 0.36
MITF O75030 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MME P08473 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CPA3 P15088 1/20 0.35
FOLH1 Q04609 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
HSD17B3 P37058 1/20 0.35
TP53 P04637 1/20 0.34
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9802357 0.70 NOTUM (0.40) NOTUMKMT2AKDM4EMAPTALDH1A1
SCHEMBL30358368 0.69 NOTUM (0.35) NOTUMKDM4EALDH1A1HSD17B3BCHE
Bromide SCHEMBL9694485 0.69 NOTUM (0.39) NOTUMKMT2AKDM4EMAPTALDH1A1
SCHEMBL16095343 0.68 NOTUM (0.40) FNTAFNTBNOTUMKMT2AKDM4E
SCHEMBL27638980 0.68 ALPI (0.40) NOTUMKMT2AMITFTDP1KDM4E
SCHEMBL16095342 0.68 NOTUM (0.40) FNTAFNTBNOTUMKMT2AKDM4E
SCHEMBL27638981 0.68 ALPI (0.40) NOTUMKMT2AMITFTDP1KDM4E
SCHEMBL1754049 0.67 NOTUM (0.53) NOTUMKMT2AMITFTDP1KDM4E
SCHEMBL5940974 0.67 MAPT (0.47) NOTUMKMT2AMITFTDP1KDM4E
Hydrochloric Acid SCHEMBL27756629 0.66 NOTUM (0.51) NOTUMKMT2AMITFTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4349468-A PENTAERYTHRITOL TETRAKIS(3-LAURYLTHIOPROPIONATE, FORMED FROM ALPHA-OLEFIN, 3-MERCAPTOPROPIONATE, AZONITRILE OR PEROXIDE CATALYST, PENTAERYTHRITOL ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-09-14 US disclosed
US-4321191-A THIO-CONTAINING POLYESTERS, POLYCARBONATES, AND COMPOUNDS; HEAT RESISTANCE; DISCOLORATION INHIBITION; MECHANICAL PROPERTIES ARGUS CHEMICAL CORP. (US) 1982-03-23 US disclosed
US-4199495-A Thiolcarbonate ester stabilizers ARGUS CHEMICAL CORP. (US) 1980-04-22 US disclosed
US-4105629-A SYNTHETIC RESIN STABILIZER COMPRISING A THIOETHER ESTER AND HINDERED PHENOLIC CARBONATE ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed
US-4080364-A Stabilization of polyolefins against degradative deterioration as a result of exposure to light and air at elevated temperatures ARGUS CHEMICAL CORPORATION (US) 1978-03-21 US disclosed