Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.50 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230230 | 0.96 | QPCT (0.51) | QPCTPRKCIALDH1A1TSHRTBXAS1 | |
| SCHEMBL11246832 | 0.95 | QPCT (0.48) | QPCTPRKCIALDH1A1TSHRTBXAS1 | |
| SCHEMBL11238443 | 0.91 | QPCT (0.49) | QPCTPRKCIALDH1A1TSHRTBXAS1 | |
| SCHEMBL11257899 | 0.91 | QPCT (0.47) | QPCTPRKCIALDH1A1KMT2ACYP19A1 | |
| SCHEMBL11242340 | 0.89 | QPCT (0.47) | QPCTPRKCIALDH1A1TSHRTBXAS1 | |
| SCHEMBL11230058 | 0.88 | TP53 (0.51) | QPCTALDH1A1TSHRTBXAS1TP53 | |
| SCHEMBL11241969 | 0.87 | CYP19A1 (0.48) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11241342 | 0.87 | MEN1 (0.55) | QPCTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11243919 | 0.86 | QPCT (0.45) | QPCTPRKCIALDH1A1TSHRMEN1 | |
| SCHEMBL11241916 | 0.85 | QPCT (0.48) | QPCTPRKCIALDH1A1TSHRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |