Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 2/20 | 0.45 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240035 | 0.86 | KMT2A (0.48) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL2020438 | 0.85 | KMT2A (0.71) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL2017369 | 0.85 | KMT2A (0.71) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL2021172 | 0.84 | KMT2A (0.70) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL6537339 | 0.82 | KMT2A (0.68) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL6293263 | 0.82 | KMT2A (0.68) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL11244456 | 0.82 | MEN1 (0.68) | KMT2AMEN1MAPT | |
| SCHEMBL6289957 | 0.82 | KMT2A (0.68) | KMT2AMEN1MAPTPOLBNPC1 | |
| SCHEMBL2719292 | 0.82 | KMT2A (0.68) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL774503 | 0.81 | MEN1 (0.67) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343804-A | 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds | A. H. ROBINS COMPANY, INC. (US) | 1982-08-10 | — | — | US | disclosed |