Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35571 | 0.91 | NR1H2 (0.65) | NR1H2NR1H3 | |
| SCHEMBL1125001 | 0.87 | NR1H2 (0.56) | NR1H2NR1H3 | |
| SCHEMBL1124744 | 0.87 | NR1H2 (0.56) | NR1H2NR1H3 | |
| SCHEMBL1125543 | 0.85 | NR1H2 (0.53) | NR1H2NR1H3 | |
| SCHEMBL1124836 | 0.85 | NR1H2 (0.53) | NR1H2NR1H3 | |
| SCHEMBL1124957 | 0.85 | NR1H2 (0.53) | NR1H2NR1H3 | |
| SCHEMBL1125073 | 0.85 | NR1H2 (0.55) | NR1H2NR1H3 | |
| SCHEMBL1125000 | 0.84 | NR1H2 (0.60) | NR1H2NR1H3 | |
| SCHEMBL27673857 | 0.84 | NR1H2 (0.60) | NR1H2NR1H3 | |
| SCHEMBL1125269 | 0.84 | NR1H2 (0.53) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2284157-A1 | Quinolines useful in treating cardiovascular disease | Wyeth (US) | 2011-02-16 | — | — | EP | disclosed |
| US-7576215-B2 | Quinolines and pharmaceutical compositions thereof | WYETH (US) | 2009-08-18 | — | — | US | disclosed |
| US-20050131014-A1 | Quinolines useful in treating cardiovascular disease | WYETH (US) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131014-A1 | Quinolines useful in treating cardiovascular disease | NR1H2, NR1H3, SREBF1 | NR1H2 1/4885NR1H3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.