Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 20/20 | 0.70 |
| ▸ | NR1H3 | Q13133 | 20/20 | 0.70 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1124758 | 0.89 | NR1H2 (0.80) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL27654085 | 0.87 | NR1H2 (0.67) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1124593 | 0.85 | NR1H2 (0.88) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL27673941 | 0.84 | NR1H2 (0.72) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL27654056 | 0.82 | NR1H2 (0.81) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1124862 | 0.82 | NR1H2 (1.00) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL27654081 | 0.82 | NR1H2 (0.69) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL27673876 | 0.81 | NR1H2 (0.79) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1124817 | 0.79 | NR1H2 (0.75) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL1125172 | 0.78 | NR1H2 (0.87) | NR1H2NR1H3PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2284157-A1 | Quinolines useful in treating cardiovascular disease | Wyeth (US) | 2011-02-16 | — | — | EP | disclosed |