Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.87 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TERT | O14746 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | F7 | P08709 | 2/20 | 0.48 |
| ▸ | F3 | P13726 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4422106 | 1.00 | MAPT (0.87) | MAPTABCC4KMT2ALMNATSHR | |
| SCHEMBL3136737 | 1.00 | MAPT (0.87) | MAPTABCC4KMT2ALMNATSHR | |
| SCHEMBL13346202 | 1.00 | MAPT (0.87) | MAPTABCC4KMT2ALMNATSHR | |
| SCHEMBL826288 | 1.00 | MAPT (0.87) | MAPTABCC4KMT2ALMNATSHR | |
| SCHEMBL3133627 | 0.96 | MAPT (0.79) | MAPTABCC4KMT2ALMNATSHR | |
| SCHEMBL823728 | 0.93 | MAPT (0.75) | MAPTABCC4KMT2ALMNATSHR | |
| Undecylenic Acid SCHEMBL17827 | 0.93 | MAPT (1.00) | MAPTABCC4KMT2ALMNATSHR | |
| SCHEMBL465896 | 0.93 | MAPT (1.00) | MAPTABCC4KMT2ALMNATSHR | |
| Undecylenic Acid SCHEMBL4464618 | 0.93 | MAPT (1.00) | MAPTABCC4KMT2ALMNATSHR | |
| Undecylenic Acid SCHEMBL5974072 | 0.93 | MAPT (1.00) | MAPTABCC4KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318914-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoro-alkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1982-03-09 | — | — | US | disclosed |
| US-4310545-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino) phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| US-4305959-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoro-alkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
| US-4205085-A | Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino)phenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1980-05-27 | — | — | US | disclosed |