Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | PPARA | Q07869 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TACR2 | P21452 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28793656 | 1.00 | TYR (0.69) | TYRTP53CYP3A4HTTMEN1 | |
| SCHEMBL31414346 | 0.98 | TYR (0.71) | TYRTP53CYP3A4HTTMEN1 | |
| SCHEMBL4961630 | 0.98 | TYR (0.71) | TYRTP53CYP3A4HTTMEN1 | |
| SCHEMBL9651371 | 0.98 | TYR (0.71) | TYRTP53CYP3A4HTTMEN1 | |
| SCHEMBL4959142 | 0.98 | TYR (0.71) | TYRTP53CYP3A4HTTMEN1 | |
| SCHEMBL4958674 | 0.98 | TYR (0.71) | TYRTP53CYP3A4HTTMEN1 | |
| SCHEMBL4960346 | 0.98 | TYR (0.71) | TYRTP53CYP3A4HTTMEN1 | |
| SCHEMBL4957861 | 0.98 | TYR (0.71) | TYRTP53CYP3A4HTTMEN1 | |
| SCHEMBL4960416 | 0.96 | TYR (0.68) | TYRTP53CYP3A4HTTMEN1 | |
| SCHEMBL83606 | 0.94 | TYR (0.69) | TYRTP53CYP3A4HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337369-A | PREPARED BY REACTION OF ISOBUTYLENE WITH ALKYLPHENOL, ION EXCHANGE RESIN CATALYST, TRIOXANE | TEXACO INC. (US) | 1982-06-29 | — | — | US | claimed |
| US-4337369-A | PREPARED BY REACTION OF ISOBUTYLENE WITH ALKYLPHENOL, ION EXCHANGE RESIN CATALYST, TRIOXANE | TEXACO INC. (US) | 1982-06-29 | — | — | US | disclosed |