Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239975 | 0.95 | KMT2A (0.48) | KMT2APOLBMEN1SMN1; SMN2LMNA | |
| SCHEMBL11236382 | 0.89 | KMT2A (0.47) | KMT2APOLBMEN1SMN1; SMN2LMNA | |
| SCHEMBL11257899 | 0.86 | QPCT (0.47) | KMT2APOLBCYP11B1CYP11B2TDP1 | |
| SCHEMBL10850943 | 0.84 | KMT2A (0.43) | KMT2APOLBMEN1SMN1; SMN2LMNA | |
| SCHEMBL11233835 | 0.84 | KMT2A (0.45) | KMT2APOLBMEN1SMN1; SMN2LMNA | |
| SCHEMBL11231289 | 0.83 | TP53 (0.48) | CYP11B1CYP11B2KDM4EHMOX1ALDH1A1 | |
| SCHEMBL11250956 | 0.83 | CYP19A1 (0.49) | POLBCYP11B1CYP11B2HMOX1QPCT | |
| SCHEMBL11241264 | 0.83 | CYP11B1 (0.49) | POLBCYP11B1CYP11B2MAPTHMOX1 | |
| SCHEMBL11237122 | 0.82 | MEN1 (0.52) | KMT2AMEN1KDM4EGAAMAPT | |
| Hydrochloric Acid SCHEMBL11240259 | 0.82 | TP53 (0.47) | CYP11B1CYP11B2KDM4EHMOX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |