SCHEMBL11248732

SCHEMBL11248732

CCCCCCCCCCCCCc1ccc2ccccc2c1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.51
ALDH1A1 P00352 4/20 0.51
GAA P10253 4/20 0.51
MAPT P10636 3/20 0.51
HPGD P15428 2/20 0.51
USP2 O75604 1/20 0.51
GLA P06280 1/20 0.51
CYP3A4 P08684 1/20 0.51
CASP1 P29466 1/20 0.51
CASP7 P55210 1/20 0.51
HSD17B10 Q99714 1/20 0.51
TLR8 Q9NR97 8/20 0.49
LIPG Q9Y5X9 1/20 0.45
NPC1 O15118 3/20 0.42
HTT P42858 3/20 0.42
RAB9A P51151 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11228143 1.00 KDM4E (0.51) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL28680926 1.00 KDM4E (0.51) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL28687866 1.00 KDM4E (0.51) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL5749122 1.00 KDM4E (0.51) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL5749879 1.00 KDM4E (0.51) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL5750251 1.00 KDM4E (0.51) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL28519758 1.00 KDM4E (0.51) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL30287368 0.98 KDM4E (0.50) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL30287338 0.98 KDM4E (0.50) KDM4EALDH1A1GAAMAPTHPGD
SCHEMBL6768325 0.98 TLR8 (0.50) KDM4EALDH1A1GAAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315756-A Oil-soluble azo dye with N-substituted β-naphthylamine as coupling component BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US disclosed
US-4067903-A Manufacture of arylamines BASF AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed