Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240201 | 0.96 | GAA (0.50) | GAAKMT2AMEN1ALOX5VCAM1 | |
| SCHEMBL18837642 | 0.95 | GAA (0.48) | GAAKMT2AMEN1ALOX5VCAM1 | |
| SCHEMBL18837623 | 0.94 | GAA (0.47) | GAAKMT2A | |
| SCHEMBL15958595 | 0.94 | GAA (0.48) | GAAKMT2AMEN1ALOX5VCAM1 | |
| SCHEMBL858491 | 0.92 | GAA (0.56) | GAAKMT2AMEN1ALOX5GMNN | |
| SCHEMBL18837621 | 0.92 | GAA (0.47) | GAAKMT2AMEN1ALOX5VCAM1 | |
| SCHEMBL18837626 | 0.92 | GAA (0.47) | GAAKMT2AMEN1ALOX5VCAM1 | |
| SCHEMBL30165 | 0.91 | GAA (0.52) | GAAKMT2AMEN1ALOX5VCAM1 | |
| SCHEMBL30331 | 0.91 | GAA (0.55) | GAAKMT2AMEN1ALOX5VCAM1 | |
| SCHEMBL20390738 | 0.91 | GAA (0.55) | GAAKMT2AMEN1ALOX5VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341879-A | Polyphenylene ether resin composition having improved heat stability and impact strength | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-07-27 | — | — | US | disclosed |