Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.51 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.51 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248919 | 0.86 | PTGDR2 (0.50) | LMNANPSR1ALDH1A1KMT2A | |
| SCHEMBL11251973 | 0.85 | RPA1 (0.50) | TP53LMNAMAPK1TSHRHSD17B10 | |
| Trifezolac SCHEMBL11182574 | 0.81 | KDM4E (0.51) | TP53LMNAMAPK1TSHRHSD17B10 | |
| SCHEMBL11249311 | 0.78 | RPA1 (0.51) | TP53LMNAALDH1A1KMT2APOLB | |
| SCHEMBL11254556 | 0.76 | PTGDR2 (0.47) | ALDH1A1KMT2ARECQL | |
| SCHEMBL11254636 | 0.76 | BCL2 (0.48) | TP53LMNAMAPK1TSHRHSD17B10 | |
| SCHEMBL11240983 | 0.76 | KMT2A (0.52) | TP53LMNAMAPK1TSHRHSD17B10 | |
| SCHEMBL11246732 | 0.76 | PTGDR2 (0.52) | TP53LMNAMAPK1TSHRHSD17B10 | |
| SCHEMBL11249520 | 0.75 | PTGDR2 (0.44) | ALDH1A1KMT2APOLB | |
| SCHEMBL1195159 | 0.75 | CYP2C9 (0.62) | TSHRALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | claimed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | claimed |
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |