Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 14/20 | 0.46 |
| ▸ | PDE5A | O76074 | 3/20 | 0.44 |
| ▸ | PDE1A | P54750 | 1/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11239003 | 0.89 | AOC3 (0.43) | AOC3PDE5APDE1APDE1BPDE1C | |
| Hydrochloric Acid SCHEMBL11247337 | 0.86 | AOC3 (0.43) | AOC3PDE5APDE1APDE1BPDE1C | |
| SCHEMBL10675326 | 0.85 | AOC3 (0.46) | AOC3PDE5APDE1APDE1BPDE1C | |
| SCHEMBL11251923 | 0.85 | GAA (0.53) | KMT2ASMN1; SMN2 | |
| SCHEMBL11239646 | 0.85 | AOC3 (0.41) | AOC3PDE5APDE1APDE1BPDE1C | |
| SCHEMBL11241637 | 0.85 | AOC3 (0.41) | AOC3PDE5APDE1APDE1BPDE1C | |
| SCHEMBL11239873 | 0.84 | AOC3 (0.47) | AOC3PDE5APDE1APDE1BPDE1C | |
| SCHEMBL9789085 | 0.84 | PDE5A (0.46) | AOC3PDE5AMAOBKMT2ASMN1; SMN2 | |
| SCHEMBL11248470 | 0.84 | KMT2A (0.43) | AOC3PDE5APDE1APDE1BPDE1C | |
| SCHEMBL6741143 | 0.84 | AOC3 (0.46) | AOC3PDE5AMAOBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362736-A | ANTISECRETORY AGENTS, GASTRIC JUICE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1982-12-07 | — | — | US | disclosed |