Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200113 | 0.89 | CCR6 (0.54) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL9814048 | 0.88 | KMT2A (0.51) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL7938727 | 0.86 | KMT2A (0.50) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL4152010 | 0.86 | KMT2A (0.56) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL3061001 | 0.86 | KMT2A (0.50) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL4152079 | 0.86 | MAPT (0.52) | MAPTKMT2AMEN1HSD17B10TP53 | |
| SCHEMBL11235620 | 0.86 | MEN1 (0.57) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL31681091 | 0.85 | MEN1 (0.68) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL4721440 | 0.85 | MEN1 (0.68) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL438878 | 0.85 | KMT2A (0.71) | MAPTKMT2AALDH1A1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751858-B | Quinolinyl-containing tranexamic acid derivative and preparation and application thereof | 沈阳药科大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-114751858-A | Quinolinyl-containing tranexamic acid derivative, preparation and application thereof | 沈阳药科大学 | 2022-07-15 | — | — | CN | disclosed |
| US-4343804-A | 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds | A. H. ROBINS COMPANY, INC. (US) | 1982-08-10 | — | — | US | disclosed |