Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21986292 | 0.92 | HTT (0.54) | HTTMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL1100395 | 0.92 | HTT (0.54) | HTTMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL11023824 | 0.89 | HTT (0.42) | HTTMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9377603 | 0.89 | HTT (0.42) | HTTMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL28739195 | 0.87 | PPARA (0.48) | HTTMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL3563040 | 0.85 | HTT (0.49) | HTTMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL10602819 | 0.85 | HTT (0.50) | HTTMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL29532511 | 0.85 | HTT (0.49) | HTTMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL29366175 | 0.85 | HTT (0.50) | HTTMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL125443 | 0.85 | HTT (0.50) | HTTMAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340514-A | RESINATES | INTERSTAB CHEMICALS INC. (US) | 1982-07-20 | — | — | US | disclosed |