SCHEMBL11250071

SCHEMBL11250071

CC1CC(C)C(CCC(=O)O)C(C)C1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.36
LMNA P02545 3/20 0.33
FFAR3 O14843 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
SLC15A2 Q16348 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.31
FOLH1 Q04609 1/20 0.31
HSD11B1 P28845 1/20 0.30
AKR1B1 P15121 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11670109 0.84
SCHEMBL10018321 0.75 KMT2A (0.46) ALOX5LMNASLC22A6FOLH1AKR1B1
SCHEMBL14979793 0.75
SCHEMBL12561189 0.75
Acetic Acid SCHEMBL11259102 0.71 EPHX2 (0.34) FFAR3
SCHEMBL9787780 0.70
SCHEMBL10600814 0.70
SCHEMBL7899750 0.68 POLB (0.32)
SCHEMBL13346650 0.68 MAPK1 (0.40) ALOX5
SCHEMBL23603713 0.68 MAPT (0.38) ALOX5LMNAFFAR3HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4321164-A 2,4,6-Trimethylcyclohexanemethanol and derivatives, process for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-03-23 US disclosed
US-4311602-A Use of 2,4,6-trimethylcyclohexanemethanol derivatives in augmenting or enhancing the aroma of dryer-added fabric softener articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-01-19 US disclosed
US-4301022-A COMPRISING THE ACETIC ACID ESTER AND THE CYCLOHEXENE COMPOUNDS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-11-17 US disclosed
US-4289146-A Use of 2,4,6-trimethylcyclohexanemethanol and derivatives for augmenting or enhancing the aroma or taste of smoking tobacco and smoking tobacco articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-09-15 US disclosed
US-4282205-A 2,4,6-Trimethylcyclohexanemethanol and derivatives, process for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-08-04 US disclosed