Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 6/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.72 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357108 | 0.84 | CYP2C9 (1.00) | CYP2C19SMN1; SMN2CYP2C9HIF1AHSPA5 | |
| SCHEMBL11247674 | 0.84 | CYP2C9 (1.00) | CYP2C19SMN1; SMN2CYP2C9HIF1AHSPA5 | |
| SCHEMBL39149 | 0.84 | CYP2C9 (1.00) | CYP2C19SMN1; SMN2CYP2C9HIF1AHSPA5 | |
| SCHEMBL34162 | 0.82 | HSPA5 (1.00) | CYP2C19SMN1; SMN2CYP2C9HIF1AHSPA5 | |
| SCHEMBL29351672 | 0.82 | HSPA5 (1.00) | CYP2C19SMN1; SMN2CYP2C9HIF1AHSPA5 | |
| SCHEMBL29415372 | 0.82 | HSPA5 (1.00) | CYP2C19SMN1; SMN2CYP2C9HIF1AHSPA5 | |
| SCHEMBL6790551 | 0.82 | CYP2C9 (0.81) | CYP2C19SMN1; SMN2CYP2C9HIF1AHSPA5 | |
| Ethylene Glycol SCHEMBL11769531 | 0.81 | HSPA5 (0.89) | CYP2C19SMN1; SMN2CYP2C9HIF1AHSPA5 | |
| SCHEMBL29410654 | 0.80 | HSPA5 (0.96) | CYP2C19SMN1; SMN2CYP2C9HIF1AHSPA5 | |
| SCHEMBL18050603 | 0.80 | SMN1; SMN2 (0.56) | CYP2C19SMN1; SMN2CYP2C9HIF1AHSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4319052-A | Method for preparing sterically hindered bis- or polyphenols | STYSKIN EVGENY L | 1982-03-09 | — | — | US | disclosed |