Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | DTYMK | P23919 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11326081 | 0.88 | TSHR (0.50) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL11447267 | 0.86 | MAPT (0.40) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL11136486 | 0.83 | PDE7A (0.38) | TSHRMAPTALDH1A1PDE7AMAPK1 | |
| SCHEMBL11483675 | 0.83 | MAPT (0.54) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL1538922 | 0.80 | MAPT (0.56) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL31038411 | 0.78 | MAPT (0.54) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL6677640 | 0.78 | MAPT (0.54) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL914291 | 0.77 | TDP1 (0.58) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL11962582 | 0.77 | TDP1 (0.50) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL11652654 | 0.77 | MAPT (0.55) | TDP1TSHRMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328241-A | ANTHELMINTICS | E. R. SQUIBB & SONS, INC. (US) | 1982-05-04 | — | — | US | disclosed |
| US-4217358-A | ANTHELMINTIC AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1980-08-12 | — | — | US | disclosed |