Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12883050 | 0.85 | PRMT5 (0.50) | PRMT5WDR77HSPA5KMT2AGAA | |
| SCHEMBL2428932 | 0.81 | NPC1 (0.45) | PRMT5WDR77HSPA5KMT2ARAB9A | |
| SCHEMBL13062490 | 0.80 | PRMT5 (0.51) | PRMT5WDR77HSPA5KMT2ARAB9A | |
| SCHEMBL12882956 | 0.80 | PRMT5 (0.48) | PRMT5WDR77HSPA5KMT2AHPGD | |
| SCHEMBL12533604 | 0.79 | PRMT5 (0.50) | PRMT5WDR77HSPA5RAB9ANPC1 | |
| SCHEMBL22303351 | 0.79 | MAPT (0.48) | HSPA5KMT2AALDH1A1MEN1 | |
| SCHEMBL28400284 | 0.79 | MAPT (0.48) | HSPA5KMT2AALDH1A1MEN1 | |
| SCHEMBL31530577 | 0.78 | PRMT5 (0.52) | PRMT5WDR77KMT2AHPGDRAB9A | |
| SCHEMBL31530575 | 0.78 | PRMT5 (0.52) | PRMT5WDR77KMT2AHPGDRAB9A | |
| SCHEMBL6663162 | 0.78 | NPC1 (0.42) | PRMT5WDR77HSPA5KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350520-A | IMIDAZOLE-2-CARBOXAMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | claimed |
| US-4350520-A | IMIDAZOLE-2-CARBOXAMIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |