SCHEMBL11253142

SCHEMBL11253142

C=CC1(C)CCC(C(C)=CCC=C(C)C)O1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 3/20 0.34
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11263760 0.77 PTPN1 (0.40) PTPN1
SCHEMBL21903096 0.75 PTPN1 (0.31) PTPN1
SCHEMBL21903091 0.75 PTPN1 (0.31) PTPN1
SCHEMBL21903081 0.75 PTPN1 (0.31) PTPN1
SCHEMBL872776 0.75 PTPN1 (0.31) PTPN1
SCHEMBL11292426 0.74 PTPN1 (0.35) PTPN1
SCHEMBL32673216 0.74 PTPN1 (0.35) PTPN1
SCHEMBL11292423 0.74 PTPN1 (0.35) PTPN1
SCHEMBL11250409 0.74 PTPN1 (0.35) PTPN1
SCHEMBL11250413 0.74 PTPN1 (0.35) PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0010142-B1 SESQUITERPENOID TETRAHYDROFURAN DERIVATIVES (I) AS ISOLATED COMPOUNDS OR IN THE FORM OF MIXTURES, PROCESS AND STARTING MATERIALS (V) FOR THEIR PREPARATION, APPLICATION OF (I) AS PERFUMES AND/OR FLAVORS AND PERFUME AND/OR FLAVOR COMPOSITIONS WITH AN AMOUNT OF (I) L. Givaudan & Cie Société Anonyme (CH) 1981-07-22 EP claimed
EP-0010142-A1 Sesquiterpenoid tetrahydrofuran derivatives (I) as isolated compounds or in the form of mixtures, process and starting materials (V) for their preparation, application of (I) as perfumes and/or flavors and perfume and/or flavor compositions with an amount of (I) L. Givaudan & Cie Société Anonyme (CH) 1980-04-30 EP claimed
US-4347190-A ORGANOLEPTIC GIVAUDAN CORPORATION (US) 1982-08-31 US disclosed
EP-0010142-B1 SESQUITERPENOID TETRAHYDROFURAN DERIVATIVES (I) AS ISOLATED COMPOUNDS OR IN THE FORM OF MIXTURES, PROCESS AND STARTING MATERIALS (V) FOR THEIR PREPARATION, APPLICATION OF (I) AS PERFUMES AND/OR FLAVORS AND PERFUME AND/OR FLAVOR COMPOSITIONS WITH AN AMOUNT OF (I) L. Givaudan & Cie Société Anonyme (CH) 1981-07-22 EP disclosed
US-4255337-A SUBSTITUTED HEXENYL TETRAHYDROFURAN GIVAUDAN CORPORATION (US) 1981-03-10 US disclosed
EP-0010142-A1 Sesquiterpenoid tetrahydrofuran derivatives (I) as isolated compounds or in the form of mixtures, process and starting materials (V) for their preparation, application of (I) as perfumes and/or flavors and perfume and/or flavor compositions with an amount of (I) L. Givaudan & Cie Société Anonyme (CH) 1980-04-30 EP disclosed