Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 2/20 | 0.41 |
| ▸ | ATP4B | P51164 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254002 | 1.00 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11260908 | 0.90 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11260899 | 0.90 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11252859 | 0.89 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11252865 | 0.89 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11244678 | 0.86 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11244685 | 0.86 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11245292 | 0.85 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL11245298 | 0.85 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL11257637 | 0.84 | MAPT (0.41) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315009-A | Antisecretory guanidine derivatives and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-02-09 | — | — | US | disclosed |