Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | PLA2G4B | P0C869 | 10/20 | 0.70 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.67 |
| ▸ | RARB | P10826 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259089 | 1.00 | TP53 (0.72) | TP53TSHRPLA2G4BPLA2G4ARARB | |
| SCHEMBL11254732 | 1.00 | TP53 (0.72) | TP53TSHRPLA2G4BPLA2G4ARARB | |
| SCHEMBL11255756 | 0.86 | MAPT (0.61) | TP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL11258392 | 0.86 | MAPT (0.61) | TP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL11241894 | 0.86 | MAPT (0.61) | TP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL3625733 | 0.85 | TP53 (1.00) | TP53TSHRPLA2G4BPLA2G4ARARB | |
| SCHEMBL503352 | 0.85 | TP53 (1.00) | TP53TSHRPLA2G4BPLA2G4ARARB | |
| SCHEMBL1163918 | 0.85 | TP53 (1.00) | TP53TSHRPLA2G4BPLA2G4ARARB | |
| SCHEMBL1469965 | 0.85 | TP53 (1.00) | TP53TSHRPLA2G4BPLA2G4ARARB | |
| SCHEMBL1322922 | 0.85 | TP53 (1.00) | TP53TSHRPLA2G4BPLA2G4ARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350822-A | Antilipidemicpara-[aryl(alkyl or alkenyl)amino]benzoic acid derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-21 | — | — | US | disclosed |
| US-4185115-A | Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives | AMERICAN CYANAMID COMPANY (US) | 1980-01-22 | — | — | US | disclosed |