Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.33 |
| ▸ | CNR1 | P21554 | 6/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255566 | 1.00 | CNR2 (0.33) | CNR2CNR1TRPA1TRPV1TSHR | |
| SCHEMBL31635596 | 0.88 | CNR2 (0.39) | CNR2CNR1TRPA1TRPV1TSHR | |
| SCHEMBL1113774 | 0.85 | — | — | |
| SCHEMBL6448438 | 0.74 | TSHR (0.40) | CNR2CNR1TRPA1TRPV1TSHR | |
| SCHEMBL6448439 | 0.74 | TSHR (0.40) | CNR2CNR1TRPA1TRPV1TSHR | |
| SCHEMBL21996121 | 0.74 | CNR2 (0.45) | CNR2CNR1TRPA1TRPV1TSHR | |
| SCHEMBL147733 | 0.72 | — | — | |
| SCHEMBL147732 | 0.72 | — | — | |
| SCHEMBL6482950 | 0.72 | — | — | |
| SCHEMBL124128 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002939-B1 | NOVEL CARBOTHIOAMIDES, COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION | ELI LILLY AND COMPANY (US) | 1982-04-21 | — | — | EP | disclosed |