Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.48 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.48 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.48 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.48 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31399941 | 0.88 | CYP1A2 (0.55) | SMN1; SMN2HTTCYP1A2GUCY1B2GUCY1A2 | |
| SCHEMBL1259501 | 0.88 | CYP1A2 (0.55) | SMN1; SMN2HTTCYP1A2GUCY1B2GUCY1A2 | |
| SCHEMBL1770090 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTCYP1A2GUCY1B2GUCY1A2 | |
| SCHEMBL16309117 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTCYP1A2GUCY1B2GUCY1A2 | |
| SCHEMBL7354309 | 0.80 | CYP1A2 (0.46) | SMN1; SMN2HTTCYP1A2GUCY1B2GUCY1A2 | |
| SCHEMBL8892306 | 0.79 | GUCY1B2 (0.50) | SMN1; SMN2HTTCYP1A2GUCY1B2GUCY1A2 | |
| SCHEMBL22288200 | 0.78 | CYP1A2 (0.54) | SMN1; SMN2HTTCYP1A2GUCY1B2GUCY1A2 | |
| SCHEMBL22288184 | 0.78 | CYP1A2 (0.54) | SMN1; SMN2HTTCYP1A2GUCY1B2GUCY1A2 | |
| SCHEMBL5873713 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTTXNRD1TXNRD3TXNRD2 | |
| SCHEMBL6311333 | 0.77 | CYP1A2 (0.46) | SMN1; SMN2HTTCYP1A2GUCY1B2GUCY1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349674-A | Quinoalinyl esters of carbamimidothioic acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |