Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 12/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247964 | 0.91 | ABCB1 (0.54) | ABCB1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11258966 | 0.90 | KDM4E (0.56) | ABCB1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11269080 | 0.90 | MEN1 (0.56) | ABCB1KDM4ECYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL11260354 | 0.89 | MEN1 (0.55) | ABCB1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11257645 | 0.89 | ABCB1 (0.56) | ABCB1KDM4EDRD2MEN1KMT2A | |
| SCHEMBL11256903 | 0.89 | ABCB1 (0.60) | ABCB1KDM4EBCHEDRD2MEN1 | |
| SCHEMBL11255351 | 0.86 | KDM4E (0.54) | KDM4ECYP1A2CYP3A4CYP2D6HTR2A | |
| SCHEMBL11255705 | 0.85 | ABCB1 (0.49) | ABCB1KDM4ECYP1A2CYP2D6DRD2 | |
| SCHEMBL11261175 | 0.84 | ABCB1 (0.62) | ABCB1DRD2 | |
| SCHEMBL11251435 | 0.83 | KDM4E (0.53) | ABCB1KDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |
| EP-0001759-A1 | (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances | MITSUBISHI KASEI CORPORATION (JP) | 1979-05-16 | — | — | EP | disclosed |