SCHEMBL11257321

SCHEMBL11257321

CCCCNC(=O)OC[C@]1(C(C)=O)C[C@@H]2C=C[C@H]1C2

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ACHE P22303 14/20 0.42
ALDH1A1 P00352 3/20 0.36
MAPT P10636 1/20 0.36
ATM Q13315 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11075848 1.00 MEN1 (0.43) MEN1KMT2AL3MBTL1ACHEALDH1A1
SCHEMBL11259323 0.96 MEN1 (0.42) MEN1KMT2AL3MBTL1ACHE
SCHEMBL11259325 0.96 MEN1 (0.42) MEN1KMT2AL3MBTL1ACHE
SCHEMBL11076629 0.95 MEN1 (0.41) MEN1KMT2AL3MBTL1ACHE
SCHEMBL11262045 0.95 MEN1 (0.41) MEN1KMT2AL3MBTL1ACHE
SCHEMBL11256657 0.93 MEN1 (0.51) MEN1KMT2AL3MBTL1ACHEALDH1A1
SCHEMBL11072312 0.93 MEN1 (0.51) MEN1KMT2AL3MBTL1ACHEALDH1A1
SCHEMBL11078115 0.89 MEN1 (0.37) MEN1KMT2AL3MBTL1ACHEALDH1A1
SCHEMBL11252005 0.88 MEN1 (0.39) MEN1KMT2AL3MBTL1ALDH1A1MAPT
SCHEMBL11252003 0.88 MEN1 (0.39) MEN1KMT2AL3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4335138-A HYPNOTIC, SEDATIVE BASF AKTIENGESELLSCHAFT (DE) 1982-06-15 US disclosed