Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266909 | 1.00 | MAPT (0.60) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11251983 | 1.00 | MAPT (0.60) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11261832 | 1.00 | MAPT (0.60) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11272655 | 1.00 | MAPT (0.60) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11270209 | 0.95 | MAPT (0.62) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11179269 | 0.91 | SMN1; SMN2 (0.63) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11256344 | 0.89 | MAPT (0.69) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11470215 | 0.88 | MAPT (0.50) | MAPTKMT2AMEN1ALDH1A1GAA | |
| Ethyl Benzoate SCHEMBL23495786 | 0.87 | SMN1; SMN2 (0.60) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11579617 | 0.86 | CA1 (0.49) | MAPTKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350822-A | Antilipidemicpara-[aryl(alkyl or alkenyl)amino]benzoic acid derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-21 | — | — | US | disclosed |
| US-4185115-A | Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives | AMERICAN CYANAMID COMPANY (US) | 1980-01-22 | — | — | US | disclosed |