Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267486 | 0.88 | TP53 (0.39) | KDM4ETP53CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11250150 | 0.88 | KMT2A (0.43) | KMT2AMEN1POLBTDP1GAA | |
| SCHEMBL11251104 | 0.88 | CYP19A1 (0.38) | KMT2AMEN1POLBMAPTCYP1A2 | |
| SCHEMBL11257033 | 0.86 | KMT2A (0.43) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL11273989 | 0.85 | KMT2A (0.50) | KMT2AMEN1POLBTDP1GAA | |
| SCHEMBL11257592 | 0.83 | KMT2A (0.48) | KMT2AMEN1POLBTDP1GAA | |
| SCHEMBL11261555 | 0.82 | KMT2A (0.40) | KMT2AMEN1POLBTDP1GAA | |
| SCHEMBL11259000 | 0.81 | KMT2A (0.45) | KMT2AMEN1POLBTDP1GAA | |
| SCHEMBL11269325 | 0.81 | KMT2A (0.45) | KMT2AMEN1POLBTDP1GAA | |
| SCHEMBL11254517 | 0.79 | QPCT (0.38) | KMT2AMEN1POLBTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |