Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP47 | Q96K76 | 6/20 | 0.52 |
| ▸ | USP7 | Q93009 | 9/20 | 0.51 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.50 |
| ▸ | USP10 | Q14694 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11458447 | 0.84 | CA1 (0.42) | USP47USP7MEN1KMT2AGPR35 | |
| SCHEMBL3880847 | 0.81 | USP10 (0.47) | USP10MAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL10252646 | 0.80 | USP47 (0.54) | USP47USP7PADI4USP10CLK1 | |
| SCHEMBL10533619 | 0.79 | USP47 (0.52) | USP47USP7PADI4USP10CLK1 | |
| SCHEMBL2681454 | 0.79 | USP7 (0.58) | USP47USP7PADI4USP10CLK1 | |
| SCHEMBL3878737 | 0.78 | USP10 (0.56) | USP10KMT2AALDH1A1 | |
| SCHEMBL10740022 | 0.76 | USP47 (0.65) | USP47USP7PADI4USP10CLK1 | |
| SCHEMBL10747018 | 0.75 | USP47 (0.52) | USP47USP7PADI4USP10CLK1 | |
| SCHEMBL10744474 | 0.75 | USP47 (0.49) | USP47USP7PADI4USP10MAPK1 | |
| SCHEMBL2681089 | 0.74 | USP7 (0.77) | USP47USP7PADI4USP10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366321-A | Preparation of 2-halo-3-nitro-5-acyl thiophenes and intermediate compounds | EASTMAN KODAK COMPANY (US) | 1982-12-28 | — | — | US | disclosed |