⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17949498 | 0.77 | — | — | |
| SCHEMBL16640706 | 0.73 | — | — | |
| SCHEMBL1276864 | 0.69 | — | — | |
| SCHEMBL43239 | 0.69 | — | — | |
| SCHEMBL10369336 | 0.69 | — | — | |
| SCHEMBL978 | 0.67 | — | — | |
| Water SCHEMBL5898983 | 0.65 | — | — | |
| SCHEMBL27839705 | 0.65 | — | — | |
| Phosphine SCHEMBL5610956 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL10616125 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10166236-B2 | Pharmaceutical formulations comprising substituted pyrazolo[5,1-c]pyrido[4,3-e][1,2,4]triazines for treating lysosomal storage disorders | PERLARA PBC (US) | 2019-01-01 | — | — | US | disclosed |
| US-20170281635-A1 | FUSED HETEROCYCLIC ORGANIC COMPOUNDS AND USES THEREOF | PERLARA PBC | 2017-10-05 | — | — | US | disclosed |
| US-9085588-B2 | Methods of preparing icotinib and icotinib hydrochloride, and intermediates thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2015-07-21 | — | — | US | disclosed |
| US-9085588-B2 | Methods of preparing icotinib and icotinib hydrochloride, and intermediates thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2015-07-21 | — | — | US | disclosed |
| US-20140343283-A1 | METHODS OF PREPARING ICOTINIB AND ICOTINIB HYDROCHLORIDE, AND INTERMEDIATES THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2014-11-20 | — | — | US | disclosed |
| US-20140343283-A1 | METHODS OF PREPARING ICOTINIB AND ICOTINIB HYDROCHLORIDE, AND INTERMEDIATES THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2014-11-20 | — | — | US | disclosed |
| EP-0049683-A2 | Imidazo-rifamycines, process for their preparation, pharmaceutical preparations containing them and their use | CIBA-GEIGY AG (CH) | 1982-04-14 | — | — | EP | disclosed |