SCHEMBL11260169

SCHEMBL11260169

[CH2]CC(=S)c1[nH]cnc1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
GABRR1 P24046 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10339806 0.78 HRH2 (0.38) KDM4E
Hydrochloric Acid SCHEMBL11400013 0.77 TDP1 (0.40) KDM4E
Bromide SCHEMBL11679776 0.77 HRH2 (0.37) KDM4E
SCHEMBL4353332 0.74
SCHEMBL828958 0.74
SCHEMBL5726855 0.67
SCHEMBL11507885 0.65
Hydrochloric Acid SCHEMBL947740 0.65 KDM4E (0.47) KDM4EGABRR1
SCHEMBL11191356 0.65
SCHEMBL5725699 0.65 KDM4E (0.40) KDM4EGABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4336394-A Cyano-ureas, cyano-thioureas and their preparation methods SOCIETE DE RECHERCHES ET DE SNYTHESES ORGAIQUES SA (CH) 1982-06-22 US disclosed
US-4336394-A Cyano-ureas, cyano-thioureas and their preparation methods SOCIETE DE RECHERCHES ET DE SNYTHESES ORGAIQUES SA (CH) 1982-06-22 US disclosed