SCHEMBL11260186

SCHEMBL11260186

Oc1cc(Cl)c(Cl)cc1Cc1ccc(Cl)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
MAPT P10636 4/20 0.65
CYP3A4 P08684 4/20 0.59
HSD17B10 Q99714 4/20 0.59
HIF1A Q16665 3/20 0.59
ALOX15 P16050 3/20 0.59
HPGD P15428 3/20 0.59
HSP90AA1 P07900 2/20 0.55
LMNA P02545 2/20 0.55
HTT P42858 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
SLC22A1 O15245 1/20 0.55
USP2 O75604 1/20 0.55
HSPD1 P10809 1/20 0.55
HSPA5 P11021 1/20 0.55
IDO1 P14902 1/20 0.55
ALOX12 P18054 1/20 0.55
CASP1 P29466 1/20 0.55
BLM P54132 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11252058 0.86 MEN1 (0.49) MEN1KMT2AMAPTCYP3A4HSD17B10
SCHEMBL27626950 0.86 HIF1A (0.79) MEN1KMT2AMAPTCYP3A4HSD17B10
SCHEMBL11255191 0.85 MEN1 (0.57) MEN1KMT2AMAPTCYP3A4HSD17B10
Dichlorophen SCHEMBL5614299 0.82 CYP3A4 (0.83) MEN1KMT2AMAPTCYP3A4HSD17B10
SCHEMBL10539465 0.82 CYP3A4 (0.63) MEN1KMT2AMAPTCYP3A4HSD17B10
SCHEMBL23227114 0.81 CYP3A4 (0.47) MEN1KMT2AMAPTCYP3A4HSD17B10
SCHEMBL30292638 0.81 CYP3A4 (0.47) MEN1KMT2AMAPTCYP3A4HSD17B10
SCHEMBL69620 0.80 CYP3A4 (0.58) MEN1KMT2AMAPTCYP3A4HSD17B10
SCHEMBL11255184 0.79 MEN1 (0.59) MEN1KMT2AMAPTCYP3A4HSD17B10
SCHEMBL875812 0.78 MEN1 (1.00) MEN1KMT2AMAPTCYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4336270-A BACTERICIDES, FUNGICIDES CIBA-GEIGY CORPORATION (US) 1982-06-22 US claimed