Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253611 | 0.90 | HRH1 (0.68) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11266783 | 0.89 | HRH1 (0.56) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11254706 | 0.89 | HRH1 (0.67) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11257755 | 0.89 | HRH1 (0.67) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11260136 | 0.89 | HRH1 (0.67) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11267177 | 0.88 | HRH1 (0.55) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11259238 | 0.88 | HRH1 (0.55) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11256434 | 0.86 | HRH1 (0.53) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11253910 | 0.85 | HRH1 (0.75) | HRH1DRD2DRD1DRD4DRD5 | |
| SCHEMBL11246969 | 0.84 | HRH1 (0.61) | HRH1DRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323568-A | INHIBIT PLATELET AGGREGATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| EP-0001759-B1 | (OMEGA-AMINOALKOXY) BIBENZYLS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE SUBSTANCES | MITSUBISHI KASEI CORPORATION (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4220603-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |