Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | MMP2 | P08253 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10918405 | 1.00 | KDM4E (0.32) | KDM4ENPSR1EPHX1CHRM2CHRM4 | |
| SCHEMBL15503230 | 0.89 | KDM4E (0.33) | KDM4ENPSR1EPHX1CHRM2CHRM4 | |
| SCHEMBL1080565 | 0.85 | SERPINE1 (0.38) | KDM4ENPSR1EPHX1MAPTSERPINE1 | |
| SCHEMBL9216168 | 0.81 | CHRM2 (0.36) | KDM4ENPSR1EPHX1CHRM2CHRM4 | |
| SCHEMBL15503284 | 0.79 | KDM4E (0.41) | KDM4ENPSR1EPHX1CHRM2CHRM4 | |
| SCHEMBL29315338 | 0.78 | CHRM2 (0.43) | KDM4ENPSR1EPHX1CHRM2CHRM4 | |
| SCHEMBL1080656 | 0.78 | SERPINE1 (0.34) | KDM4ENPSR1EPHX1SLC6A3MAPT | |
| SCHEMBL5836544 | 0.77 | SERPINE1 (0.32) | SERPINE1 | |
| SCHEMBL6892499 | 0.77 | SERPINE1 (0.32) | SERPINE1 | |
| SCHEMBL6892502 | 0.77 | SERPINE1 (0.32) | SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332729-A | CATALYZED CYCLIZATION | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | disclosed |