Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1C | Q14123 | 1/20 | 0.74 |
| ▸ | CACNA1C | Q13936 | 11/20 | 0.59 |
| ▸ | CACNA1F | O60840 | 10/20 | 0.59 |
| ▸ | CACNA1D | Q01668 | 10/20 | 0.59 |
| ▸ | CACNA1S | Q13698 | 10/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258636 | 0.90 | CACNA1C (0.72) | PDE1CCACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL11268103 | 0.87 | CACNA1C (0.67) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL11393485 | 0.86 | PDE1C (0.70) | PDE1CCACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL11259313 | 0.86 | CACNA1C (0.61) | PDE1CCACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL11252846 | 0.85 | CACNA1F (0.56) | PDE1CCACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL11257924 | 0.85 | CACNA1F (0.59) | PDE1CCACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL11258513 | 0.85 | CACNA1F (0.75) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL11271363 | 0.84 | CACNA1F (0.63) | PDE1CCACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL11258726 | 0.83 | MEN1 (0.64) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL11263102 | 0.83 | NR3C2 (0.66) | PDE1CCACNA1CCACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |