Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11264349 | 0.99 | MAPT (0.45) | MAPTNPC1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11261115 | 0.87 | MAPT (0.51) | MAPTNPC1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11271738 | 0.84 | MAPT (0.48) | MAPTNPC1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11253932 | 0.82 | MAPT (0.46) | MAPTNPC1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11266789 | 0.82 | MAPT (0.46) | MAPTNPC1ALDH1A1LMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL11262657 | 0.81 | MAPT (0.46) | MAPTNPC1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11253904 | 0.80 | MAPT (0.49) | MAPTNPC1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11262352 | 0.80 | MAPT (0.49) | MAPTNPC1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11266127 | 0.79 | MAPT (0.49) | MAPTNPC1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11259854 | 0.79 | SMN1; SMN2 (0.52) | MAPTNPC1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | claimed |
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |