Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278421 | 1.00 | KMT2A (0.51) | KMT2AKDM4EMAPTHSP90AA1FAAH | |
| SCHEMBL11264555 | 1.00 | KMT2A (0.51) | KMT2AKDM4EMAPTHSP90AA1FAAH | |
| SCHEMBL11265815 | 1.00 | KMT2A (0.51) | KMT2AKDM4EMAPTHSP90AA1FAAH | |
| SCHEMBL11276917 | 0.93 | MAPT (0.50) | KMT2AKDM4EMAPTHSP90AA1FAAH | |
| SCHEMBL11267205 | 0.87 | MAPT (0.43) | KMT2AKDM4EMAPTHSP90AA1FAAH | |
| SCHEMBL1573059 | 0.81 | HSP90AA1 (0.61) | KMT2AKDM4EMAPTHSP90AA1FAAH | |
| SCHEMBL9410605 | 0.81 | HSP90AA1 (0.61) | KMT2AKDM4EMAPTHSP90AA1FAAH | |
| SCHEMBL29147871 | 0.81 | HSP90AA1 (0.61) | KMT2AKDM4EMAPTHSP90AA1FAAH | |
| SCHEMBL20724956 | 0.81 | HSP90AA1 (0.61) | KMT2AKDM4EMAPTHSP90AA1FAAH | |
| SCHEMBL9410595 | 0.81 | HSP90AA1 (0.61) | KMT2AKDM4EMAPTHSP90AA1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |