Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10865467 | 1.00 | — | — | |
| Bromide SCHEMBL9451029 | 0.87 | — | — | |
| Bromide SCHEMBL27470970 | 0.87 | — | — | |
| Bromide SCHEMBL10457047 | 0.82 | — | — | |
| Bromide SCHEMBL11503584 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6352272 | 0.82 | — | — | |
| Bromide SCHEMBL3454710 | 0.82 | — | — | |
| Bromide SCHEMBL1032276 | 0.82 | — | — | |
| Bromide SCHEMBL1030524 | 0.82 | — | — | |
| Bromide SCHEMBL1029370 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054924-A2 | Pharmaceutical compounds, their preparation and use | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-06-30 | — | — | EP | disclosed |
| EP-0022229-A1 | Substituted phenol ethers, their preparation, intermediates therefor, pharmaceutical compositions containing them and the preparation thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-01-14 | — | — | EP | disclosed |