Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.53 |
| ▸ | RPA1 | P27694 | 8/20 | 0.51 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254556 | 0.86 | PTGDR2 (0.47) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11255212 | 0.86 | PTGDR2 (0.54) | KDM4EALDH1A1CYP1A2GAACYP2D6 | |
| Trifezolac SCHEMBL11182574 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11249550 | 0.83 | CA1 (0.58) | PTGDR2 | |
| SCHEMBL11699362 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1CYP1A2GAACYP2C9 | |
| SCHEMBL11254211 | 0.81 | CA1 (0.53) | KDM4EALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11250252 | 0.81 | CNR1 (0.51) | PTGDR2 | |
| SCHEMBL11246732 | 0.81 | PTGDR2 (0.52) | KDM4EALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11257118 | 0.81 | PTGDR2 (0.54) | KDM4EALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11243360 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1CYP1A2GAACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |